Just before you go into combat in PvP, talk to the guy who runs the store where you buy inspirations.
With the store open, have your inspiration slot's open.
Buy a full stock of damage buffs, use them all.
Now buy another full stock and buy them as well. Be sure you do this very quickly.
Do the same thing with Insight's and you will be a killing machine. Whenever I do this with my scrapper or my blaster, I get one hit kill's on extreme damage attack's. It works even better for stalker's because if you are hidden you automatically get a critical hit.